【How-to】What does it mean if your hematocrit is high

Bone pain as the presenting symptom in polycythemia vera (PV) is rare, especially without the diagnosis of myelofibrosis (MF). Pain, however, can manifest as a late symptom in approximately 50% of patients with the diagnosis. The cause of pain has been attributed to hematopoiesis, periostitis, and osteosclerosis.